E3 UBIQUITIN LIGASE MARCH5 POSITIVELY REGULATES JAPANESE ENCEPHALITIS VIRUS INFECTION BY CATALYZING THE K27-LINKED POLYUBIQUITINATION OF VIRAL E PROTEIN AND INHIBITING MAVS-MEDIATED TYPE I INTERFERON PRODUCTION

ABSTRACT Membrane-associated RING-CH-type finger (MARCH) proteins, a class of E3 ubiquitin ligases, have been reported to be involved in the infection of multiple viruses and the regulation of type I interferon (IFN) production.However, the specific role and mechanisms by which MARCH proteins influence Japanese encephalitis virus (JEV) infection re

Communication is an important aspect that involves interaction between teachers and students in the hope that the message will be well received and have an impact on understanding and changes in behavior.This research aims to analyze teacher-student communication in the educational process at MIN 2 Banjar.The method used is descriptive qualitative

The objective of this study was to carry out a systematic quality review and meta-analysis of Hemp Wicks all literature published in years 1981-1997 which studied the effect of drugs in the elderly and which had analyzable data on major groups of drugs.The sources of data were reports of surveys, case-control, prospective and retrospective studies,

At present, a GLUCOSAJOINT significant share, up to 50% of the marketing budget, is spent on Internet and social media campaigns focusing on community involvement rather than mere content sharing.Social media sites such as Facebook, YouTube, and Instagram provide an open environment where teasers, behind-the-scenes content, polls, competitions, and

Gear system is characterized by high efficiency, compact structure, and transmission ratio stability, and it has been extensively applied in various industrial equipment.This paper presents a novel preliminary estimate method for gear reducer noise radiation and vibration characteristics, and systematic researches on radiation characteristics of ge